No it shouldn't be a problem. As long as the first and last name plus the date of birth is correct I am sure that they will just view it as a typo.
Obviously I don't know what airline you are travelling with but many don't even put the prefix on the ticket.
It might be worth contacting the airline to check but to be honest it is The Secure Flight Passenger Data that counts which is name, date of birth and gender.
As your date of birth and name will match the records I can't see why they would be worried by it, mistakes happen.
However, I would hate for you to get to the airport and find out that you can't travel, so just to be safe, I would call them and ask the question. If worst comes to worst maybe you could cancel the tickets and start again.