The most obvious answer is your own kids:
But after that, here's the top 5 worst things to leave at home when going on vacation:Credit Card/Money
Nothing worse than putting your hand into your pocket to pay for all the duty free goods at the airport when you realize you have no money on you. Bad way to start a vacation.
Passports
There's nothing like missing your flight because you forgot your passports at home.
Interestingly, this guy was allowed to cross the US-Canada border with a photo of his passport on his iPad. No fair!
Phone
Speaking of technology, leaving your phone at home is also something most people would regret. Yes, you want to relax and get away from it all.. But seriously? No phone?!?
Charger
This is literally an extension of the previous item. Leaving for the holidays without a charger means you will be seeing a whole lot of this on your travels:
Keys
Often, people don't even realize they've forgotten their keys until they get back home at 2am in the morning: Cold and tired and just wanting to get back home and into bed.