It is 150 miles.  There are many companies that offer day tours.
                    
                
            
                    
        
                  242 km / 150 miles
                
        
                  Weve done it before by train  from st agnelo forgive spelling  pompeii one day then rome next
                                    
                            
        
                  Multimap says 242 km / 150 miles / about 2.5 hours in the car.
Multimap directions and route map.
Googlemaps France says more than 3 hours, and 243 km of driving. Google routemap is easier to see than Multimap's, but I can't link directly to it.
That's assuming you don't get lost and Italian cities are notorious for absent street signs, as well as very hectic and confusing traffic.
        
                  Multimap directions and route map.
Googlemaps France says more than 3 hours, and 243 km of driving. Google routemap is easier to see than Multimap's, but I can't link directly to it.
That's assuming you don't get lost and Italian cities are notorious for absent street signs, as well as very hectic and confusing traffic.