If you approximate the distance from the middle of the United States to the UK, the total distance from USA to UK is 4,333 miles. This is equivalent to 6,974 kilometers or 3,766 nautical miles.
I'd say approx. 4, 330 miles really...
The distance between USA and UK cannot be determined as such because the value will be different from different parts of the border. In order to get the correct distance choose two cities from both the countries, and find the distance between them. Use the following city distance tool to calculate the distance.